Very common (10% or more): Nausea (up to 34%), Vomiting (up to 15%)Ĭommon (1% to 10%): Abdominal pain, diarrhea, constipation, dyspepsia, enlarged abdomenįrequency not reported: Dry mouth Hypersensitivity Rare (less than 0.1%): Increased hepatic transaminasesįrequency not reported: Liver failure Gastrointestinal HepaticĬommon (1% to 10%): Increased aspartate aminotransferase Injection site pain and injection site reaction have been reported with the IV product. The most commonly reported adverse reactions have included nausea, vomiting, constipation. In general, acetaminophen is well-tolerated when administered in therapeutic doses. swelling, pain, or tenderness in the upper abdomen or stomach areaĪpplies to acetaminophen: compounding powder, intravenous solution, oral capsule, oral granule effervescent, oral liquid, oral powder, oral powder for reconstitution, oral suspension, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release, rectal suppository.Get emergency help immediately if any of the following symptoms of overdose occur while taking acetaminophen: Symptoms of overdose sores, ulcers, or white spots on the lips or in the mouth.sore throat (not present before treatment and not caused by the condition being treated).pain in the lower back and/or side (severe and/or sharp). fever with or without chills (not present before treatment and not caused by the condition being treated).Although not all of these side effects may occur, if they do occur they may need medical attention.Ĭheck with your doctor immediately if any of the following side effects occur while taking acetaminophen: Rare Other dosage forms:Īlong with its needed effects, acetaminophen may cause some unwanted effects. Continue reading for a comprehensive list of adverse effects.Īpplies to acetaminophen: capsule, capsule liquid filled, elixir, liquid, powder, solution, suppository, suspension, tablet, tablet chewable, tablet disintegrating, tablet extended release. More frequently reported side effects include: fever. If those who take acetaminophen regularly notice higher blood pressure readings, they should reduce their dosage or discuss with their doctor.Medically reviewed by. Yet, it's best to use the lowest effective dose, and no more than two regular-strength (325-mg) tablets every six hours, or two extra-strength (500-mg) tablets every eight hours. This doesn't mean people with hypertension should never take acetaminophen for aches and pains. The results showed that in people who used high-dose acetaminophen, systolic blood pressure (the top number) increased about five points more than those who took a placebo. Blood pressure was measured before and after each treatment period. After allowing time for the drugs to leave their system, they took the other type of pill for another two weeks. Researchers randomized 110 hypertension patients with no chronic pain to take either 1,000 milligrams (mg) of acetaminophen or a placebo four times daily for two weeks. 8, 2022, issue of Circulation suggests acetaminophen might have the same effect. Acetaminophen (Tylenol) is often the pain reliever of choice for people with high blood pressure (hypertension) because most other options are types of nonsteroidal anti-inflammatory drugs like ibuprofen (Motrin, Advil) or naproxen (Naprosyn, Aleve), which can raise blood pressure.
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